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Metabolic abnormalities in adult T-cell leukemia/lymphoma and induction of specific leukemic cell death using photodynamic therapy

Adult T-cell leukemia/lymphoma (ATL) is an aggressive T-cell neoplasm caused by human T-cell leukemia virus type I (HTLV-I). Therapeutic interventions have not been associated with satisfactory outcomes. We showed that the porphyrin metabolic pathway preferentially accumulates the endogenous photose...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oka, Takashi, Mizuno, Hajime, Sakata, Masumi, Fujita, Hirofumi, Yoshino, Tadashi, Yamano, Yoshihisa, Utsumi, Kozo, Masujima, Tsutomu, Utsunomiya, Atae
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175925/
https://ncbi.nlm.nih.gov/pubmed/30297858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33175-7
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