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Efficacy of l-Ornithine l-Aspartate for the Treatment of Hepatic Encephalopathy and Hyperammonemia in Cirrhosis: Systematic Review and Meta-Analysis of Randomized Controlled Trials

BACKGROUND/OBJECTIVES: l-Ornithine l-Aspartate (LOLA) is a mixture of two endogenous amino acids with the capacity to fix ammonia in the form of urea and/or glutamine. Its’ efficacy for the treatment of Hepatic Encephalopathy (HE), a known hyperammonemic disorder, remains the subject of debate. This...

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Pubblicato in:J Clin Exp Hepatol
Autori principali: Butterworth, Roger F., Kircheis, Gerald, Hilger, Norbert, McPhail, Mark J.W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175748/
https://ncbi.nlm.nih.gov/pubmed/30302048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jceh.2018.05.004
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