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Free fatty acids reduce metabolic stress and favor a stable production of heterologous proteins in Pichia pastoris

The growth of yeasts in culture media can be affected by many factors. For example, methanol can be metabolized by other pathways to produce ethanol, which acts as an inhibitor of the heterologous protein production pathway; oxygen concentration can generate aerobic or anaerobic environments and aff...

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Detalles Bibliográficos
Publicado en:Braz J Microbiol
Main Authors: Zepeda, Andrea B., Figueroa, Carolina A., Pessoa, Adalberto, Farías, Jorge G.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175731/
https://ncbi.nlm.nih.gov/pubmed/29705163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bjm.2018.03.008
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