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A Distributed Classifier for MicroRNA Target Prediction with Validation through TCGA Expression Data

BACKGROUND: MicroRNAs (miRNAs) are approximately 22-nucleotide long regulatory RNA that mediate RNA interference by binding to cognate mRNA target regions. Here, we present a distributed kernel SVM-based binary classification scheme to predict miRNA targets. It captures the spatial profile of miRNA-...

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Detalhes bibliográficos
Publicado no:IEEE/ACM Trans Comput Biol Bioinform
Main Authors: Ghoshal, Asish, Zhang, Jinyi, Roth, Michael A., Xia, Kevin Muyuan, Grama, Ananth, Chaterji, Somali
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175706/
https://ncbi.nlm.nih.gov/pubmed/29993641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TCBB.2018.2828305
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