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An information theoretic treatment of sequence-to-expression modeling

Studying a gene’s regulatory mechanisms is a tedious process that involves identification of candidate regulators by transcription factor (TF) knockout or over-expression experiments, delineation of enhancers by reporter assays, and demonstration of direct TF influence by site mutagenesis, among oth...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Autores principales: Khajouei, Farzaneh, Sinha, Saurabh
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175532/
https://ncbi.nlm.nih.gov/pubmed/30256780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006459
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