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RNAi screening identifies a new Toll from shrimp Litopenaeus vannamei that restricts WSSV infection through activating Dorsal to induce antimicrobial peptides

The function of Toll pathway defense against bacterial infection has been well established in shrimp, however how this pathway responds to viral infection is still largely unknown. In this study, we report the Toll4-Dorsal-AMPs cascade restricts the white spot syndrome virus (WSSV) infection of shri...

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Publicado en:PLoS Pathog
Autores principales: Li, Haoyang, Yin, Bin, Wang, Sheng, Fu, Qihui, Xiao, Bang, Lǚ, Kai, He, Jianguo, Li, Chaozheng
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175524/
https://ncbi.nlm.nih.gov/pubmed/30256850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007109
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