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Adolescent binge ethanol-induced loss of basal forebrain cholinergic neurons and neuroimmune activation are prevented by exercise and indomethacin

Basal forebrain cholinergic neurons mature in adolescence coinciding with development of adult cognitive function. Preclinical studies using the rodent model of adolescent intermittent ethanol (AIE; 5.0 g/kg, i.g., 2-days on/2-days off from postnatal day [P]25 to P55) reveal persistent increases of...

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Bibliographic Details
Published in:PLoS One
Main Authors: Vetreno, Ryan P., Crews, Fulton T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175501/
https://ncbi.nlm.nih.gov/pubmed/30296276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204500
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