A characterization of postzygotic mutations identified in monozygotic twins

Postzygotic mutations are DNA changes acquired from the zygote stage onwards throughout the lifespan. These changes lead to differences in DNA sequence among cells of an individual, potentially contributing to the etiology of complex disorders. Here we compared whole genome DNA sequence data of two...

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Bibliografske podrobnosti
izdano v:Hum Mutat
Main Authors: Ouwens, Klaasjan G., Jansen, Rick, Tolhuis, Bas, Slagboom, P. Eline, Penninx, Brenda W.J.H., Boomsma, Dorret I.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175188/
https://ncbi.nlm.nih.gov/pubmed/29980163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23586
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