Maintenance dose conversion between oral risperidone and paliperidone palmitate 1 month: Practical guidance based on pharmacokinetic simulations

AIM: We assessed the dosage strengths of paliperidone palmitate 1‐month (PP1M) long‐acting injectable resulting in similar steady‐state (SS) exposures to the dosage strengths of oral risperidone using pharmacokinetic (PK) simulations. METHODS: Population PK simulations of SS PK were performed using...

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Dettagli Bibliografici
Pubblicato in:Int J Clin Pract
Autori principali: Russu, Alberto, Kern Sliwa, Jennifer, Ravenstijn, Paulien, Singh, Arun, Mathews, Maju, Kim, Edward, Gopal, Srihari
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Psychiatry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175146/
https://ncbi.nlm.nih.gov/pubmed/29707876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ijcp.13089
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