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In vivo characterization of four (68)Ga-labelled multimeric RGD peptides to image α(v)β(3) integrin expression in two human tumour xenograft mouse models

RATIONALE: α(v)β(3) integrins play an important role in angiogenesis and cell migration of tumours. They are highly expressed on activated endothelial cells of newly formed blood vessels. Here, we compare the targeting characteristics of four (68)Ga-labelled multimeric cyclic RGD-based tracers in an...

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Bibliographic Details
Published in:J Nucl Med
Main Authors: Lobeek, Daphne, Franssen, Gerben M., Ma, Michelle T., Wester, Hans-Jürgen, Decristoforo, Clemens, Oyen, Wim J. G., Boerman, Otto C., Terry, Samantha Y. A., Rijpkema, Mark
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175042/
https://ncbi.nlm.nih.gov/pubmed/29626124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.117.206979
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