Cross-Reactivity and Anti-viral Function of Dengue Capsid and NS3-Specific Memory T Cells Toward Zika Virus

Zika virus (ZIKV), a flavivirus with homology to dengue virus (DENV), is spreading to areas of DENV hyper-endemicity. Heterologous T cell immunity, whereby virus-specific memory T cells are activated by variant peptides derived from a different virus, can lead to enhanced viral clearance or diminish...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lim, Mei Qiu, Kumaran, Emmanuelle A. P., Tan, Hwee Cheng, Lye, David C., Leo, Yee Sin, Ooi, Eng Eong, MacAry, Paul A., Bertoletti, Antonio, Rivino, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174860/
https://ncbi.nlm.nih.gov/pubmed/30327651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02225
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