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Improving the Reliability and Utility of Streptozotocin-Induced Rat Diabetic Model

The Streptozotocin- (STZ-) induced diabetic model is widely used; however, unexplained acute toxicity has given the model an unreliable reputation. To improve the reliability and utility of this model, we characterize the age dependence of STZ toxicity and introduce novel endpoints to assess diabeti...

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Podrobná bibliografie
Vydáno v:J Diabetes Res
Hlavní autoři: Wang-Fischer, Yanlin, Garyantes, Tina
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174751/
https://ncbi.nlm.nih.gov/pubmed/30345315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8054073
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