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Calcium-Induced Stabilization of AU-Rich Short-Lived mRNAs Is a Common Default Response
The AU-rich element (AUUUA)(n), found in the 3′ noncoding region of many short-lived cytokine and proto-oncogene mRNAs, is sufficient to specifically target these mRNAs for rapid degradation in mammalian cells. The mechanism by which the AU-rich element promotes rapid mRNA decay is not known. Previo...
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| Publicado no: | Gene Expr |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cognizant Communication Corporation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6174662/ https://ncbi.nlm.nih.gov/pubmed/10440236 |
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