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Functional Role of p21 During the Cellular Response to Stress

A wide range of stress stimuli, including oxidants, genotoxins, metabolic deficiencies, and irradiation, have been shown to induce expression of the cyclin-dependent kinase inhibitor p21. Among the best characterized mediators of p21 induction by stress is the tumor suppressor gene p53, which acts a...

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Bibliographic Details
Published in:Gene Expr
Main Authors: Gorospe, Myriam, Wang, Xiantao, Holbrook, Nikki J.
Format: Artigo
Language:Inglês
Published: Cognizant Communication Corporation 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174658/
https://ncbi.nlm.nih.gov/pubmed/10440238
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