The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue

Macrophages are highly versatile cells, which acquire, depending on their microenvironment, pro- (M1-like), or antiinflammatory (M2-like) phenotypes. Here, we studied the role of the G-protein coupled receptor G2A (GPR132), in chemotactic migration and polarization of macrophages, using the zymosan-...

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Udgivet i:Front Immunol
Main Authors: Kern, Katharina, Schäfer, Stephan M. G., Cohnen, Jennifer, Pierre, Sandra, Osthues, Tabea, Tarighi, Neda, Hohmann, Stefan, Ferreiros, Nerea, Brüne, Bernhard, Weigert, Andreas, Geisslinger, Gerd, Sisignano, Marco, Scholich, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174245/
https://ncbi.nlm.nih.gov/pubmed/30327654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02261
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