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The Relationship Between Population Attributable Fraction and Heritability in Genetic Studies

Population attributable fraction (PAF) has been widely used to quantify the proportion of disease risk in a population that can be attributed to risk factors in epidemiological studies. However, the use of PAF has been limited in assessing the contribution of genetic variants. Most notably, the PAF...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Wang, Tao, Hosgood, H. Dean, Lan, Qing, Xue, Xiaonan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174220/
https://ncbi.nlm.nih.gov/pubmed/30327663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00352
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