Intraperitoneal Nanotherapy for Metastatic Ovarian Cancer Based on siRNA-Mediated Suppression of DJ-1 Protein Combined with a Low Dose of Cisplatin

Herein, we report an efficient combinatorial therapy for metastatic ovarian cancer based on siRNA-mediated suppression of DJ-1 protein combined with a low dose of cisplatin. DJ-1 protein modulates, either directly or indirectly, different oncogenic pathways that support and promote survival, growth,...

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Publicat a:Nanomedicine
Autors principals: Schumann, Canan, Chan, Stephanie, Millar, Jess A., Bortnyak, Yuliya, Carey, Katherine, Fedchyk, Alex, Wong, Leon, Korzun, Tetiana, Moses, Abraham S., Lorenz, Anna, Shea, Delany, Taratula, Olena, Khalimonchuk, Oleh, Taratula, Oleh
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174103/
https://ncbi.nlm.nih.gov/pubmed/29635082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2018.03.005
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