Transient High Pressure in Pancreatic Ducts Promotes Inflammation and Alters Tight Junctions via Calcineurin Signaling in Mice

BACKGROUND AND AIMS: Pancreatitis following endoscopic retrograde cholangiopancreatography (PEP) is thought to be provoked by pancreatic ductal hypertension, via unknown mechanisms. We investigated the effects of hydrostatic pressures on the development of pancreatitis in mice. METHODS: We performed...

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Publicado en:Gastroenterology
Autores principales: Wen, Li, Javed, Tanveer A., Yimlamai, Dean, Mukherjee, Amitava, Xiao, Xiangwei, Husain, Sohail Z.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174093/
https://ncbi.nlm.nih.gov/pubmed/29928898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.06.036
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