Methotrexate is not superior to placebo in maintaining steroid-free response or remission in ulcerative colitis

BACKGROUND & AIMS: Parenteral methotrexate induces clinical remission but not endoscopic improvement of mucosal inflammation in patients with ulcerative colitis (UC). We performed a randomized, placebo-controlled trial to assess the efficacy of parenteral methotrexate in maintaining steroid-free...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Herfarth, Hans, Barnes, Edward L, Valentine, John F, Hanson, John, Higgins, Peter DR, Isaacs, Kim L, Jackson, Susan, Osterman, Mark T, Anton, Kristen, Ivanova, Anastasia, Long, Millie D, Martin, Chris, Sandler, Robert S, Abraham, Bincy, Cross, Raymond K, Dryden, Gerald, Fischer, Monika, Harlan, William, Levy, Campbell, McCabe, Robert, Polyak, Steven, Saha, Sumona, Williams, Emmanuelle, Yajnik, Vijay, Serrano, Jose, Sands, Bruce E, Lewis, James D
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174092/
https://ncbi.nlm.nih.gov/pubmed/29964043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.06.046
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