Alternative Splicing Rewires Hippo Signaling Pathway in Hepatocytes to Promote Liver Regeneration

During liver regeneration, most new hepatocytes arise via self-duplication; yet, the underlying mechanisms that drive hepatocyte proliferation following injury remain poorly defined. By combining high-resolution transcriptome- and polysome-profiling of hepatocytes purified from quiescent and toxin-i...

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Bibliografiske detaljer
Udgivet i:Nat Struct Mol Biol
Main Authors: Bangru, Sushant, Arif, Waqar, Seimetz, Joseph, Bhate, Amruta, Chen, Jackie, Rashan, Edrees H., Carstens, Russ P., Anakk, Sayeepriyadarshini, Kalsotra, Auinash
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173981/
https://ncbi.nlm.nih.gov/pubmed/30250226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0129-2
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