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Determination of ED50 and time to effectiveness for intrathecal hydromorphone in laboring patients using Dixon’s up-and-down sequential allocation method

BACKGROUND: With the increasing occurrence of drug shortages, understanding the pharmacokinetics of alternative intrathecal opioid administration has gained importance. In particular, additional data are needed to comprehensively evaluate the analgesic properties of intrathecal hydromorphone in the...

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Bibliografische gegevens
Gepubliceerd in:BMC Anesthesiol
Hoofdauteurs: O’Reilly-Shah, Vikas, Lynde, Grant C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173834/
https://ncbi.nlm.nih.gov/pubmed/30290794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-018-0603-8
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