BRCA1 and BRCA2 mRNA-expression prove to be of clinical impact in ovarian cancer

BACKGROUND: Mutations in BRCA1 and BRCA2 are associated with better survival in ovarian cancer (OC) patients due to a better response to platinum-based chemotherapy. However, the impact of the BRCA1/2 mRNA-expression is not well characterized in OC. PATIENTS AND METHODS: We investigated BRCA1/2 mRNA...

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Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Tsibulak, Irina, Wieser, Verena, Degasper, Christine, Shivalingaiah, Giridhar, Wenzel, Sören, Sprung, Susanne, Lax, Sigurd F., Marth, Christian, Fiegl, Heidelinde, Zeimet, Alain G.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173779/
https://ncbi.nlm.nih.gov/pubmed/30111871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0217-4
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