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A new pharmacokinetic model for (90)Y-ibritumomab tiuxetan based on 3-dimensional dosimetry

Monoclonal antibodies (mAbs) are key components in several therapies for cancer and inflammatory diseases but current knowledge of their clinical pharmacokinetics and distribution in human tissues remains incomplete. Consequently, optimal dosing and scheduling in clinics are affected. With sequentia...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Morschhauser, F., Dekyndt, B., Baillet, C., Barthélémy, C., Malek, E., Fulcrand, J., Bigot, P., Huglo, D., Décaudin, B., Simon, N., Odou, P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173718/
https://ncbi.nlm.nih.gov/pubmed/30291297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33160-0
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