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A Jagged 1–Notch 4 molecular switch mediates airway inflammation induced by ultrafine particles

BACKGROUND: Exposure to traffic-related particulate matter (PM) promotes asthma and allergic diseases. However, the precise cellular and molecular mechanisms by which PM exposure acts to mediate these effects remain unclear. OBJECTIVE: We sought to elucidate the cellular targets and signaling pathwa...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Xia, Mingcan, Harb, Hani, Saffari, Arian, Sioutas, Constantinos, Chatila, Talal A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173656/
https://ncbi.nlm.nih.gov/pubmed/29627423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.03.009
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