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Long-Term Clinical Outcomes of High-Dose Mepolizumab Treatment for Hypereosinophilic Syndrome

BACKGROUND: Conventional therapies for hypereosinophilic syndromes (HES) have variable efficacy and carry significant long-term toxicities. Anti-IL-5 (mepolizumab) therapy has a glucocorticoid (GC)-sparing effect in GC-sensitive HES, but the efficacy of mepolizumab in treatment-refractory HES patien...

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Bibliographische Detailangaben
Veröffentlicht in:J Allergy Clin Immunol Pract
Hauptverfasser: Kuang, Fei Li, Fay, Michael P., Ware, JeanAnne, Wetzler, Lauren, Holland-Thomas, Nicole, Brown, Thomas, Ortega, Hector, Steinfeld, Jonathan, Khoury, Paneez, Klion, Amy D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173586/
https://ncbi.nlm.nih.gov/pubmed/29751154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaip.2018.04.033
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