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Genomic Feature Selection by Coverage Design Optimization

We introduce a novel data reduction technique whereby we select a subset of tiles to “cover” maximally events of interest in large-scale biological datasets (e.g., genetic mutations), while minimizing the number of tiles. A tile is a genomic unit capturing one or more biological events, such as a se...

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Detalles Bibliográficos
Publicado en:J Appl Stat
Autores principales: Reid, Stephen, Newman, Aaron M., Diehn, Maximilian, Alizadeh, Ash A., Tibshirani, Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173524/
https://ncbi.nlm.nih.gov/pubmed/30294060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02664763.2018.1432577
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