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Lp-PLA(2), scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease

BACKGROUND: We previously reported association of SCARB1 SNP rs10846744 with common carotid IMT (cIMT) and cardiovascular disease (CVD) events. Since rs10846744 has been reported in association with Lp-PLA(2) mass and activity, we hypothesized that inflammatory pathways might mediate the association...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Manichaikul, Ani, Wang, Xin-Qun, Li, Li, Erdmann, Jeanette, Lettre, Guillaume, Bis, Joshua C., Waterworth, Dawn, Cushman, Mary, Jenny, Nancy S., Post, Wendy S., Palmas, Walter, Tsai, Michael Y., Wallentin, Lars, White, Harvey, Schunkert, Heribert, O’Donnell, Christopher J., Herrington, David M., Rich, Stephen S., O’Donoghue, Michelle L., Rodriguez, Annabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173398/
https://ncbi.nlm.nih.gov/pubmed/30289950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204352
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