In vitro and ex-vivo evaluation of topical formulations designed to minimize transdermal absorption of Vitamin K1

Topical application of Vitamin K1 has been demonstrated to effectively treat papulopustular skin rash, a serious and frequently encountered side effect of Epidermal Growth Factor Inhibitors (EGFRIs). Systemic absorption of vitamin K1 from skin and the resultant consequence of antagonizing EGFRIs ant...

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Vydáno v:PLoS One
Hlavní autoři: Nabiee, Ramina, Dubois, Barent, Green, Laura, Sharma, Ajay, Wong, Siu Fun, Montazeri Aliabadi, Hamidreza
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173387/
https://ncbi.nlm.nih.gov/pubmed/30289881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204531
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