Generation and characteristics of a novel “double-hit” high grade B-cell lymphoma cell line DH-My6 with MYC/IGH and BCL6/IGH gene arrangements and potential molecular targeted therapies

“Double-hit” lymphoma (DHL) is a high-grade B-cell lymphoma that harbors concurrent MYC and BCL2 or BCL6 rearrangements. Because cases of MYC/BCL6 DHL are uncommon, most reported conclusions have been based on cases of MYC/BCL2 DHL. Lack of experimental MYC/BCL6 DHL models continues to hinder the pa...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kikuchi, Hiroaki, Higuchi, Tomonori, Hashida, Yumiko, Taniguchi, Ayuko, Kamioka, Mikio, Taguchi, Takahiro, Yokoyama, Akihito, Murakami, Ichiro, Fujieda, Mikiya, Daibata, Masanori
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173362/
https://ncbi.nlm.nih.gov/pubmed/30323893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26060
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