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Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines

Within populations carrying the same genetic predisposition, the penetrance of BRCA1 mutations has increased over time. Although linked to changes in lifestyle factors associated with energy metabolism, these observations cannot be explained by the established role of BRCA1 in DNA repair alone. We m...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Koobotse, Moses, Holly, Jeff, Perks, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173354/
https://ncbi.nlm.nih.gov/pubmed/30323899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26093
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