Cargando...
Protease-activated Receptor 1 Activation Enhances Doxorubicin-induced Cardiotoxicity
OBJECTIVE: The anti-cancer anthracycline drug Doxorubicin (Dox) causes cardiotoxicity. We investigated the role of protease-activated receptor 1 (PAR-1) in Dox-induced cardiotoxicity. METHODS AND RESULTS: In vitro experiments revealed that PAR-1 enhanced Dox-induced mitochondrial dysfunction, reacti...
Gardado en:
| Publicado en: | J Mol Cell Cardiol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6173317/ https://ncbi.nlm.nih.gov/pubmed/30098988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.08.008 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|