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Hypoxic stabilization of mRNA is HIF-independent but requires mtROS

BACKGROUND: Tissue ischemia can arise in response to numerous physiologic and pathologic conditions. The cellular response to decreased perfusion, most notably a decrease in glucose and oxygen, is important for cellular survival. In response to oxygen deprivation or hypoxia, one of the key response...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Fortenbery, Grey W, Sarathy, Brinda, Carraway, Kristen R, Mansfield, Kyle D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172842/
https://ncbi.nlm.nih.gov/pubmed/30305827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-018-0112-2
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