Inhibition of WEE1 Suppresses the Tumor Growth in Laryngeal Squamous Cell Carcinoma

WEE1 is a tyrosine kinase that regulates G2/M cell cycle checkpoint and frequently overexpressed in various tumors. However, the expression and clinical significance of WEE1 in human laryngeal squamous cell carcinoma (LSCC) are still unknown. In this study, we found that WEE1 was highly expressed in...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Yuan, Meng-Ling, Li, Pei, Xing, Zi-Hao, Di, Jin-Ming, Liu, Hui, Yang, An-Kui, Lin, Xi-Jun, Jiang, Qi-Wei, Yang, Yang, Huang, Jia-Rong, Wang, Kun, Wei, Meng-Ning, Li, Yao, Ye, Jin, Shi, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172786/
https://ncbi.nlm.nih.gov/pubmed/30323762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01041
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