Combination of pristimerin and paclitaxel additively induces autophagy in human breast cancer cells via ERK1/2 regulation

Pristimerin, a quinonemethide triterpenoid, has demonstrated anticancer activity against a number of types of cancer, including breast cancer. However, its mechanism of action remains unclear. The present study investigated the autophagy-induced anticancer efficacy of pristimerin on MDA-MB-231 human...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Lee, Younju, Na, Jinuk, Lee, Myung Sun, Cha, Eun Young, Sul, Ji Young, Park, Jun Beom, Lee, Jin Sun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172393/
https://ncbi.nlm.nih.gov/pubmed/30221728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9488
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