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Epigallocatechin-3 gallate prevents pressure overload-induced heart failure by up-regulating SERCA2a via histone acetylation modification in mice

Heart failure is a common, costly, and potentially fatal condition. The cardiac sarcoplasmic reticulum Ca-ATPase (SERCA2a) plays a critical role in the regulation of cardiac function. Previously, low SERCA2a expression was revealed in mice with heart failure. Epigallocatechin-3-gallate (EGCG) can fu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Lifei, Zhao, Weian, Liu, Jianxia, Gan, Yi, Liu, Lingjuan, Tian, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171916/
https://ncbi.nlm.nih.gov/pubmed/30286210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205123
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