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High tension in sarcomeres hinders myocardial relaxation: A computational study
Experiments have shown that the relaxation phase of cardiac sarcomeres during an isometric twitch is prolonged in muscles that reached a higher peak tension. However, the mechanism is not completely understood. We hypothesize that the binding of calcium to troponin is enhanced by the tension in the...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6171862/ https://ncbi.nlm.nih.gov/pubmed/30286135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204642 |
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