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Development of standard clinical endpoints for use in dengue interventional trials

Dengue is a major public health problem worldwide. Although several drug candidates have been evaluated in randomized controlled trials, none has been effective and at present, early recognition of severe dengue and timely supportive care are used to reduce mortality. While the first dengue vaccine...

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Bibliografiske detaljer
Udgivet i:PLoS Negl Trop Dis
Main Authors: Tomashek, Kay M., Wills, Bridget, See Lum, Lucy Chai, Thomas, Laurent, Durbin, Anna, Leo, Yee-Sin, de Bosch, Norma, Rojas, Elsa, Hendrickx, Kim, Erpicum, Martin, Agulto, Liane, Jaenisch, Thomas, Tissera, Hasitha, Suntarattiwong, Piyarat, Collers, Beth Ann, Wallace, Derek, Schmidt, Alexander C., Precioso, Alexander, Narvaez, Federico, Thomas, Stephen J., Edelman, Robert, Siqueira, João Bosco, Cassetti, M. Cristina, Dempsey, Walla, Gubler, Duane J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171842/
https://ncbi.nlm.nih.gov/pubmed/30286085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006497
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