Impaired monocyte cholesterol clearance initiates age-related retinal degeneration and vision loss

Advanced age-related macular degeneration (AMD), the leading cause of blindness among people over 50 years of age, is characterized by atrophic neurodegeneration or pathologic angiogenesis. Early AMD is characterized by extracellular cholesterol-rich deposits underneath the retinal pigment epitheliu...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Ban, Norimitsu, Lee, Tae Jun, Sene, Abdoulaye, Choudhary, Mayur, Lekwuwa, Michael, Dong, Zhenyu, Santeford, Andrea, Lin, Jonathan B., Malek, Goldis, Ory, Daniel S., Apte, Rajendra S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171801/
https://ncbi.nlm.nih.gov/pubmed/30185655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120824
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