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Gestational diabetes and maternal obesity are associated with epigenome-wide methylation changes in children

Offspring of women with gestational diabetes mellitus (GDM) are at increased risk of developing metabolic disease, potentially mediated by epigenetic mechanisms. We recruited 608 GDM and 626 control offspring from the Danish National Birth Cohort, aged between 9 and 16 years. DNA methylation profile...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Hjort, Line, Martino, David, Grunnet, Louise Groth, Naeem, Haroon, Maksimovic, Jovana, Olsson, Anders Henrik, Zhang, Cuilin, Ling, Charlotte, Olsen, Sjurdur Frodi, Saffery, Richard, Vaag, Allan Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171795/
https://ncbi.nlm.nih.gov/pubmed/30185669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122572
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