Metronomic Four-Drug Regimen Has Anti-tumor Activity in Pediatric Low-Grade Glioma; The Results of a Phase II Clinical Trial

Background: Metronomic chemotherapy (MC) is defined as the frequent administration of chemotherapy at doses below the maximal tolerated dose and with no prolonged drug-free break. MC has shown its efficacy in adult tumor types such as breast and ovarian cancer and has to some extent been studied in...

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Veröffentlicht in:Front Pharmacol
Hauptverfasser: Verschuur, Arnauld, Heng-Maillard, Marie-Amélie, Dory-Lautrec, Philippe, Truillet, Romain, Jouve, Elisabeth, Chastagner, Pascal, Leblond, Pierre, Aerts, Isabelle, Honoré, Stéphane, Entz-Werle, Natasha, Sirvent, Nicolas, Gentet, Jean-Claude, Corradini, Nadège, André, Nicolas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171442/
https://ncbi.nlm.nih.gov/pubmed/30319400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00950
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