High-Risk Acute Promyelocytic Leukemia with Unusual T/Myeloid Immunophenotype Successfully Treated with ATRA and Arsenic Trioxide-Based Regimen

We describe two patients with acute promyelocytic leukemia (APL) with an unusual immunophenotype with co-expression of myeloperoxidase (MPO) with cytoplasmic CD3 (cCD3) representing myeloid and T-lineage differentiation. Both harbored FLT3-ITD mutations. One additionally had a deletion in the PML ge...

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Pubblicato in:J Hematop
Autori principali: Singh, Zeba N., Duong, Vu H., Koka, Rima, Zou, Ying, Sawhney, Sameer, Tang, Li, Baer, Maria R., Ambulos, Nicholas, El Chaer, Firas, Emadi, Ashkan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171103/
https://ncbi.nlm.nih.gov/pubmed/30294391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12308-018-0329-z
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