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Insulin resistance disrupts cell integrity, mitochondrial function and inflammatory signaling in lymphatic endothelium

OBJECTIVE: Lymphatic vessel dysfunction and increased lymph leakage have been directly associated with several metabolic diseases. However, the underlying cellular mechanisms causing lymphatic dysfunction have not been determined. Aberrant insulin signaling affects the metabolic function of cells, a...

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Publicat a:Microcirculation
Autors principals: Lee, Yang, Chakraborty, Sanjukta, Meininger, Cynthia J., Muthuchamy, Mariappan
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170722/
https://ncbi.nlm.nih.gov/pubmed/30025187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12492
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