A novel Pd-catalysed sequential carbonylation/cyclization approach toward bis-N-heterocycles: rationalization by electronic structure calculations

An unprecedented palladium-catalysed sequential aminocarbonylation/cyclization synthetic strategy, using carbon monoxide and structurally different aliphatic diamines as N-nucleophiles, gives access, in one pot, to a new family of indole-based N-heterocyclic derivatives (hydropyrazinones, benzodiaze...

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Publicado en:R Soc Open Sci
Autores principales: Damas, Liliana, Carrilho, Rui M. B., Nunes, Sandra C. C., Pais, Alberto A. C. C., Kollár, László, Pineiro, Marta, Pereira, Mariette M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2018
Materias:
Chemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170558/
https://ncbi.nlm.nih.gov/pubmed/30839738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.181140
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