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Transient receptor potential channel 6 knockdown prevents apoptosis of renal tubular epithelial cells upon oxidative stress via autophagy activation

Reactive oxygen species (ROS) are generated under various pathological conditions such as renal ischemia/reperfusion (I/R) injury and provoke damage to multiple cellular organelles and processes. Overproduction of ROS causes oxidative stress and contributes to damages of renal proximal tubular cells...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Hou, Xin, Xiao, Haitao, Zhang, Yanhong, Zeng, Xixi, Huang, Mengjun, Chen, Xiaoyun, Birnbaumer, Lutz, Liao, Yanhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170481/
https://ncbi.nlm.nih.gov/pubmed/30282964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1052-5
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