Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia

High-throughput sequencing was applied to investigate the mutation/methylation patterns on 1q and gene expression profiles in pediatric B-cell precursor acute lymphoblastic leukemia (BCP ALL) with/without (w/wo) dup(1q). Sequencing of the breakpoint regions and all exons on 1q in seven dup(1q)-posit...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Gunnarsson, Rebeqa, Dilorenzo, Sebastian, Lundin-Ström, Kristina B, Olsson, Linda, Biloglav, Andrea, Lilljebjörn, Henrik, Rissler, Marianne, Wahlberg, Per, Lundmark, Anders, Castor, Anders, Behrendtz, Mikael, Fioretos, Thoas, Paulsson, Kajsa, Isaksson, Anders, Johansson, Bertil
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170391/
https://ncbi.nlm.nih.gov/pubmed/29626196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0092-2
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