Regulatory cocktail for dopaminergic neurons in a protovertebrate identified by whole-embryo single-cell transcriptomics

The CNS of the protovertebrate Ciona intestinalis contains a single cluster of dopaminergic (DA) neurons, the coronet cells, which have been likened to the hypothalamus of vertebrates. Whole-embryo single-cell RNA sequencing (RNA-seq) assays identified Ptf1a as the most strongly expressed cell-speci...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Horie, Takeo, Horie, Ryoko, Chen, Kai, Cao, Chen, Nakagawa, Masashi, Kusakabe, Takehiro G., Satoh, Noriyuki, Sasakura, Yasunori, Levine, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169837/
https://ncbi.nlm.nih.gov/pubmed/30228204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.317669.118
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