Recurrent aseptic meningitis with PIGT mutations: a novel pathogenesis of recurrent meningitis successfully treated by eculizumab

We report the case of a patient with PIGT mutations who experienced recurrent aseptic meningitis 121 times over 16 years before developing paroxysmal nocturnal haemoglobinuria (PNH). Each episode was preceded by urticaria and arthralgia. After developing PNH, haemolysis occurred prior to meningitis....

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Detalhes bibliográficos
Publicado no:BMJ Case Rep
Main Authors: Kawamoto, Michi, Murakami, Yoshiko, Kinoshita, Taroh, Kohara, Nobuo
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169622/
https://ncbi.nlm.nih.gov/pubmed/30262533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2018-225910
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