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Mimicking Co-Transcriptional RNA Folding Using a Superhelicase
Vectorial folding of RNA during transcription can produce intermediates with distinct biochemical activities. Here, we design an artificial minimal system to mimic co-transcriptional RNA folding in vitro. In this system, a pre-synthesized RNA molecule begins to fold from its 5’-end, as it is release...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6169520/ https://ncbi.nlm.nih.gov/pubmed/30063835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b03784 |
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