Light modulation ameliorates expression of circadian genes and disease progression in spinal muscular atrophy mice

Physiology and behaviour are critically dependent on circadian regulation via a core set of clock genes, dysregulation of which leads to metabolic and sleep disturbances. Metabolic and sleep perturbations occur in spinal muscular atrophy (SMA), a neuromuscular disorder caused by loss of the survival...

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Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Walter, Lisa M, Koch, Christiane E, Betts, Corinne A, Ahlskog, Nina, Meijboom, Katharina E, van Westering, Tirsa L E, Hazell, Gareth, Bhomra, Amarjit, Claus, Peter, Oster, Henrik, Wood, Matthew J A, Bowerman, Melissa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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General Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168969/
https://ncbi.nlm.nih.gov/pubmed/29982483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy249
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