SERPINE1 IDENTIFIED AS POTENTIAL THERAPEUTIC TARGET THROUGH RNA-SEQ OF CLINICALLY RELEVANT INVASIVE GLIOBLASTOMA CELLS ISOLATED FROM PATIENTS BY 5-ALA BASED METHODOLOGY

INTRODUCTION: We previously described a method to separate residual tumour cells from normal brain using fluorescent activated cell sorting (FACS). Using RNA-Seq on these cells we have identified new potential targets including SERPINE1, whose expression remains high in tumour cells as they invade i...

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Publicado no:Neuro Oncol
Main Authors: Rowlinson, Jonathan, de los Angeles Estevez-Cebrero, Maria, Lourdusamy, Anbarasu, Rahman, Ruman, Smith, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168812/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy129.020
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