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SERPINE1 IDENTIFIED AS POTENTIAL THERAPEUTIC TARGET THROUGH RNA-SEQ OF CLINICALLY RELEVANT INVASIVE GLIOBLASTOMA CELLS ISOLATED FROM PATIENTS BY 5-ALA BASED METHODOLOGY
INTRODUCTION: We previously described a method to separate residual tumour cells from normal brain using fluorescent activated cell sorting (FACS). Using RNA-Seq on these cells we have identified new potential targets including SERPINE1, whose expression remains high in tumour cells as they invade i...
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| Yayımlandı: | Neuro Oncol |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6168812/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy129.020 |
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